“我們必須要跳出原有概念，即認為癌症只是橫行細胞的一個隨機集合體，”賴斯大學理論生物物理（CTBP）研究中心主任Herbert Levine說，這篇文章公佈在Cell出版社旗下的Trends in Microbiology雜誌上，並作為封面文章推薦。這項研究匯總了近期關於癌細胞的幾十篇研究論文，探索了癌細胞社會性行為。
原文摘要：Bacterial survival strategies suggest rethinking cancer cooperativity
Despite decades of a much improved understanding of cancer biology, we are still baffled by questions regarding the deadliest traits of malignancy: metastatic colonization, dormancy and relapse, and the rapid evolution of multiple drug and immune resistance. New ideas are needed to resolve these critical issues. Relying on finding and demonstrating parallels between collective behavior capabilities of cancer cells and that of bacteria, we suggest communal behaviors of bacteria as a valuable model system for new perspectives and research directions. Understanding the ways in which bacteria thrive in competitive habitats and their cooperative strategies for surviving extreme stress can shed light on cooperativity in tumorigenesis and portray tumors as societies of smart communicating cells. This may translate into progress in fathoming cancer pathogenesis. We outline new experiments to test the cancer cooperativity hypothesis and reason that cancer may be outsmarted through its own social intelligence.
